1.02307

α-Chymotrypsin from bovine pancreas

cryst. lyophilized 350 U/mg for biochemistry

• Código UNSPSC: 12352204
• NACRES: NA.21

Propriedades

• Formulário: solid
• potência: >4000 mg/kg LD₅₀, oral (rat)
• pH: 3-5 (10 g/L in H₂O)

Descrição

Descrição geral

α-Chymotrypsin (CT) is a member of the S1 family. It comprises a catalytic triad system including aspartate, histidine, and serine. It is produced by chymotrypsinogen in the pancreas and then secreted into the digestive tract.

Aplicação

α-Chymotrypsin has been used to study its adsorption characteristics on solid/liquid interfaces under varying adsorption conditions.

Ações bioquímicas/fisiológicas

α-Chymotrypsin (CT) closely denotes a group of digestive enzymes (trypsin, elastase) that hydrolyzes polypeptide chains. The catalytic triad system works together to regulate the nucleophilicity of the serine residue in catalysis. CT shows a capability to catalyze nonconventional synthetic reactions in water-miscible organic media. Additionally, it is also used as a tool in comparative studies of water-miscible and water-immiscible solvents.

Características e benefícios

• Easily obtainable due to small size
• Relatively stable

Nota de análise

Appearance (description):lyophilisate
Appearance (colour):slightly yellowish
Activity (ATEE, pH 8.0, 25 °C):≥ 350 U/mg
Spec. activity (calc. on protein):ca. 400

Informações de segurança

• Pictogramas: GHS07,GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H302 - H315 - H319 - H334 - H335 - H400
• Declarações de precaução: P261 - P273 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1