06-1376

Anti-SLBP Antibody

serum, from rabbit

• Sinônimo(s): Histone stem-loop-binding protein, hairpin binding protein, histone binding protein 2, histone stem-loop binding protein, stem-loop (histone) binding protein, stem-loop binding protein, HBP, Histone RNA hairpin-binding protein
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: serum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• reatividade de espécies: mouse, human
• reatividade da espécie (prevista por homologia): rat
• técnica(s): immunocytochemistry: suitable; western blot: suitable
• nº de adesão NCBI: NM_009193
• nº de adesão UniProt: P97440
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SLBP(7884)

Descrição

Descrição geral

The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3′ end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Especificidade

Antibody recognizes SLBP.

Imunogênio

KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP.

Aplicação

Immunocytochemistry:
Representative lot data.
Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus.

Research Sub Category
RNA Metabolism & Binding Proteins

Histones

Use Anti-SLBP Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect SLBP also known as Histone stem-loop-binding protein, HBP, Histone RNA hairpin-binding protein.

Qualidade

Evaluated by Western Blotting in C2C12 cell lysates.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates.

Descrição-alvo

38 kDa

forma física

Serum in buffer containing 0.05% sodium azide

Nota de análise

Control
C2C12 cell lysates.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1