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05-382

Sigma-Aldrich

Anti-Na+/K+ ATPase β-1 Antibody, clone C464.8

clone C464.8, Upstate®, from mouse

Sinônimo(s):

Anti-AHC2, Anti-ATP1A1, Anti-CAPOS, Anti-DEE99, Anti-DYT12, Anti-RDP

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

C464.8, monoclonal

reatividade de espécies

rabbit, bovine, canine, human, rat

fabricante/nome comercial

Upstate®

técnica(s)

immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG2aκ

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... ATP1A3(478)

Descrição geral

Clone C464.8 is also referred to as clone 8A

Especificidade

Recognizes the β-1 subunit isoform of Na+/K+.

Imunogênio

Purified Na+/K+ ATPase isolated from membrane fractions of rabbit kidney outer medulla.

Aplicação

Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-Na+/K+ ATPase β-1 Antibody, clone C464.8 is validated for use in IH, WB for the detection of Na+/K+ ATPase β-1.

Qualidade

routinely evaluated in immunoblot on rat brain, rat heart or rat kidney microsomal preparations

Descrição-alvo

broad band at an apparent molecular weight of 48-55 kDa due to glycosylation

forma física

Format: Purified
Protein G Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in PBS with 0.05% sodium azide before the addition of glycerol to 30%

Armazenamento e estabilidade

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análise

Control
Expressed in most tissue, including brain, heart and kidney

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.
Lee J Martin,Zhiping Liu,Kevin Chen,Ann C Price,Yan Pan,Jason A Swaby,W Christopher Golden
The Journal of Comparative Neurology null
Man Liang et al.
The Journal of biological chemistry, 282(14), 10585-10593 (2007-02-14)
Recent studies have ascribed many non-pumping functions to the Na/K-ATPase. Here, we present experimental evidence demonstrating that over half of the plasma membrane Na/K-ATPase in LLC-PK1 cells is performing cellular functions other than ion pumping. This "non-pumping" pool of Na/K-ATPase
Regional distribution of Na,K-ATPase activity in porcine lens epithelium
Tamiya, S., et al
Investigative Ophthalmology & Visual Science, 44, 4395-4399 (2003)
Thyroid hormone stimulates Na-K-ATPase activity and its plasma membrane insertion in rat alveolar epithelial cells.
Jianxun Lei, Sogol Nowbar, Cary N Mariash, David H Ingbar
American Journal of Physiology. Lung Cellular and Molecular Physiology null
An ion-transporting ATPase encodes multiple apical localization signals.
Gottardi, C J and Caplan, M J
The Journal of cell biology, 121, 283-293 (1993)

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