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Documentos Principais

04-539

Sigma-Aldrich

Anti-MAPKAP-K2 Antibody, clone 7H4.2

clone 7H4.2, Upstate®, from mouse

Sinônimo(s):

MAPK-activated protein kinase 2, MAPKAP kinase 2

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100

forma do anticorpo

purified antibody

tipo de produto de anticorpo

primary antibodies

clone

7H4.2, monoclonal

reatividade de espécies

human, rat, mouse

fabricante/nome comercial

Upstate®

técnica(s)

immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

nº de adesão NCBI

NM_004759.3
NM_032960.2

nº de adesão UniProt

P49137

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... MAPKAPK2(9261)

Imunogênio

KLH-conjugated synthetic peptide of the C-terminus of the long form of human MAPKAP-K2.

Aplicação

Suggested dilutions:
Immunoblot Analysis: 1:500
Immunoprecipitation: 1:20
Anti-MAPKAP-K2 Antibody, clone 7H4.2 detects level of MAPKAP-K2 & has been published & validated for use in IP & WB.
Research Category
Signaling
Research Sub Category
MAP Kinases

Kinases & Phosphatases

Qualidade

Routinely evaluated by immunoblot.

Descrição-alvo

45 kDa

forma física

200 µg (1 mg/mL) of mouse monoclonal IgG in PBS containing 0.1% sodium azide.
Format: Purified
Protein A purified

Armazenamento e estabilidade

2 years at -20°C from date of shipment.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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L Xu et al.
Oncogene, 25(21), 2987-2998 (2006-01-13)
Although cell invasion is a necessary early step in cancer metastasis, its regulation is not well understood. We have previously shown, in human prostate cancer, that transforming growth factor beta (TGFbeta)-mediated increases in cell invasion are dependent upon activation of
Isaac A Manke et al.
Molecular cell, 17(1), 37-48 (2005-01-05)
The cellular response to DNA damage is mediated by evolutionarily conserved Ser/Thr kinases, phosphorylation of Cdc25 protein phosphatases, binding to 14-3-3 proteins, and exit from the cell cycle. To investigate DNA damage responses mediated by the p38/stress-activated protein kinase (SAPK)
Ainsley A Culbert et al.
The Journal of biological chemistry, 281(33), 23658-23667 (2006-06-16)
MAPK-activated protein kinase 2 (MAPKAP K2 or MK2) is one of several kinases directly regulated by p38 MAPK. A role for p38 MAPK in the pathology of Alzheimer disease (AD) has previously been suggested. Here, we provide evidence to suggest
Matthieu Lemaire et al.
Cell cycle (Georgetown, Tex.), 5(15), 1649-1653 (2006-07-25)
CDC25B is one of the three human phosphatases that are involved in the control of the activation of cyclin-dependent kinases. CDC25B participates in regulating entry into mitosis and appears to play a key role in the checkpoint response to DNA

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