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Merck
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Key Documents

P-906

Supelco

Prazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C19H17ClN2O
Número CAS:
Peso molecular:
324.80
Número CE:
Código UNSPSC:
41116107
NACRES:
NA.24

grau

certified reference material

Nível de qualidade

forma

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentração

1.0 mg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

clinical testing

formato

single component solution

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Clc1ccc2N(CC3CC3)C(=O)CN=C(c4ccccc4)c2c1

InChI

1S/C19H17ClN2O/c20-15-8-9-17-16(10-15)19(14-4-2-1-3-5-14)21-11-18(23)22(17)12-13-6-7-13/h1-5,8-10,13H,6-7,11-12H2

chave InChI

MWQCHHACWWAQLJ-UHFFFAOYSA-N

Descrição geral

Prazepam is a benzodiazepine prescribed for the short-term treatment of anxiety. Sold under the trade name Centrax, this drug also has anticonvulsant, sedative, and muscle relaxant effects. This Snap-N-Spike® Reference Solution is suitable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, or forensic analysis.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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M Soyka et al.
Der Nervenarzt, 65(9), 628-632 (1994-09-01)
We report the case of a 61-year old patient with an affective disorder who had been treated with benzodiazepines in low dosages over a 16 year period. This treatment had been prescribed by his physician following several depressive episodes. During
X H Chen et al.
Journal of chromatography, 617(1), 147-151 (1993-07-23)
The lot-to-lot reproducibilities of Bond Elut Certify and Clean Screen DAU columns are described. The recoveries of five test drugs obtained from twelve lots of Bond Elut Certify columns ranged from 84 to 104% with standard deviations of less than
H L Tai et al.
Clinical biochemistry, 26(3), 165-171 (1993-06-01)
A simple, rapid high-pressure liquid chromatography (HPLC) method was developed for detecting and quantifying benzodiazepines in serum. Seven major benzodiazepines were extracted from spiked serum samples using solid-phase extraction with prazepam as the internal standard. The eluted drugs were then
François-Ludovic Sauvage et al.
Journal of separation science, 32(18), 3074-3083 (2009-08-22)
LC coupled to single (LC-MS) and tandem (LC-MS/MS) mass spectrometry is recognized as the most powerful analytical tools for metabolic studies in drug discovery. In this article, we describe five cases illustrating the utility of screening xenobiotic metabolites in routine
H A Archontaki et al.
Journal of pharmaceutical and biomedical analysis, 17(4-5), 739-750 (1998-07-31)
A reversed-phase HPLC method was developed for the kinetic investigation of the acidic hydrolysis of prazepam which was carried out in hydrochloric acid solutions of 0.01, 0.1 and 1.0 M. In addition, a fourth-order derivative method for monitoring the parent

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