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N-003

Supelco

Norcocaine hydrochloride solution

1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C16H19NO4 · HCl
Número CAS:
61585-22-6
Peso molecular:
325.79
Número MDL:
MFCD00242703
Código UNSPSC:
41116107
ID de substância PubChem:
329818391
NACRES:
NA.24

grau

certified reference material

Formulário

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in acetonitrile (as free base)

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

forensics and toxicology

Formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cl.COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1OC(=O)c3ccccc3)N2

InChI

1S/C16H19NO4.ClH/c1-20-16(19)14-12-8-7-11(17-12)9-13(14)21-15(18)10-5-3-2-4-6-10;/h2-6,11-14,17H,7-9H2,1H3;1H/t11-,12+,13-,14+;/m0./s1

chave InChI

RIPPXFWUYXTRNJ-BHARVXRSSA-N

Descrição geral

Norcocaine is a primary urinary metabolite of the popular recreation drug cocaine. Cocaine is a central nervous system stimulant with appetite suppressant and topical anesthetic properties. This certified solution standard is applicable for use in urine drug testing, clinical toxicology or forensic toxicology applications by GC/MS or LC/MS.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictogramas

FlameExclamation mark
GHS02,GHS07

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

35.6 °F - closed cup

Ponto de fulgor (°C)

2 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number

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Kathleen M Kantak
Expert opinion on pharmacotherapy, 4(2), 213-218 (2003-02-04)
The past decade has seen the development of several vaccines against illicit-drugs. These include vaccines for producing antibodies against cocaine, heroin, methamphetamine and nicotine. The present focus is on anti-cocaine vaccines, as more research has been conducted with these vaccines
C W Schindler et al.
European journal of pharmacology, 431(1), 53-59 (2001-11-22)
The effects of cocaine and the cocaine metabolites norcocaine, ecgonine methyl ester, benzoylecgonine and cocaethylene were evaluated in conscious squirrel monkeys for their effects on blood pressure and heart rate. Norcocaine, ecgonine methyl ester and benzoylecgonine are produced in vivo
Christine Moore et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 859(2), 208-212 (2007-10-24)
A quantitative analytical procedure for the determination of cocaine, benzoylecgonine and cocaethylene and norcocaine in hair has been developed and validated. The hair samples were washed, incubated, and any drugs present were quantified using mixed mode solid-phase extraction and liquid
Hsiu-Li Su et al.
Electrophoresis, 29(20), 4270-4276 (2008-10-17)
We have employed a high-sensitivity on-line preconcentration method, cation-selective exhaustive injection (CSEI) and sweeping MEKC, for the analysis of cocaine, benzoylecgonine, norcocaine, and cocaethylene. We monitored the effects of several of the CSEI-sweeping-MEKC parameters - including the pH, the concentrations
P Pellinen et al.
Archives of toxicology, 74(9), 511-520 (2000-12-29)
The first step in the oxidative metabolism of cocaine is N-demethylation to norcocaine, which is further N-hydroxylated to more toxic N-hydroxynorcocaine. In this study we examined the kinetics of norcocaine N-hydroxylation mediated by cytochrome P450 (CYP) in mouse and human
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