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M-078

Supelco

2-Mononitroglycerin solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C3H7NO5
Número CAS:
620-12-2
Peso molecular:
137.09
Número MDL:
MFCD01075379
Código UNSPSC:
41116107
ID de substância PubChem:
329817830
NACRES:
NA.24

grau

certified reference material

Nível de qualidade

300

Formulário

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in acetonitrile

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

pharmaceutical (small molecule)

Formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OCC(CO)O[N+]([O-])=O

InChI

1S/C3H7NO5/c5-1-3(2-6)9-4(7)8/h3,5-6H,1-2H2

chave InChI

QYZBMMOLPVKAPU-UHFFFAOYSA-N

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Descrição geral

2-Mononitroglycerin is a major plasma metabolite of the pharmaceutical vasodilator nitroglycerin. This Certified Spiking Solution® is suitable for use in chromatography or mass spectrometry-based applications in pharmaceutical research or clinical toxicology. Nitroglycerin is used to treat heart conditions such as angina and chronic heart failure.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictogramas

FlameExclamation mark
GHS02,GHS07

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

35.6 °F - closed cup

Ponto de fulgor (°C)

2 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number

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M Leitold et al.
Arzneimittel-Forschung, 37(6), 692-698 (1987-06-01)
Glyceryl 2-nitrate (G-2-N), which is the major metabolite of glyceryl trinitrate (GTN, Nitro Mack, glyceryl 1-nitrate (G-1-N) and isosorbide-5-nitrate (IS-5-N, Mono Mack) were examined in a comparative study. The haemodynamic and antianginal properties and the spasmolytic activity on blood vessels
C Ducrocq et al.
Biotechnology and applied biochemistry, 12(3), 325-330 (1990-06-01)
Various microorganisms have been evaluated for their ability to hydrolyze glyceryl trinitrate (GTN) to glyceryl dinitrates and mononitrates. Provided that the GTN extracellular concentration was under the lethal dose, metabolite formation and regioselectivity depend on the nature of the strain
M Leitold et al.
Arzneimittel-Forschung, 36(12), 1752-1756 (1986-12-01)
Comparative Hemodynamic Activity of Glyceryl 2-Nitrate and Glyceryl Trinitrate in Various Species and Pharmacokinetics of Glyceryl 2-Nitrate in Dog A single dose of glyceryl 2-nitrate (G-2-N) had practically identical hypotensive and cardiovascular activity when administered intravenously or enterally to the
E Malta
Clinical and experimental pharmacology & physiology, 16(11), 829-835 (1989-11-01)
1. The present study has examined the possibility that one or more metabolites of glyceryl trinitrate (GTN) (i.e. glyceryl-1,2- and -1,3-dinitrate and glyceryl-1- and -2-mononitrate) may be responsible for the second phase of the biphasic relaxant curve to GTN in

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