Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

C-117

Supelco

Corticosterone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Fórmula empírica (Notação de Hill):
C21H30O4
Número CAS:
Peso molecular:
346.46
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material

Nível de qualidade

forma

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

clinical testing
clinical testing

formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO

InChI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

chave InChI

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

Descrição geral

Corticosterone is a corticosteroid and aldosterone precursor produced in the adrenal glands. Serum corticosterone levels are measured by LC-MS/MS for newborn screening and diagnosis of 11-hydroxylase deficiency.

Aplicação


  • Corticosterone ELISA kit for stress hormone research: Research has demonstrated the efficacy of corticosterone ELISA kits in measuring stress hormone levels, contributing significantly to studies on adrenal gland function and stress-related disorders. This application is vital for in vivo corticosterone analysis, allowing detailed monitoring of hormone fluctuations in response to various stressors (Ornelas et al., 2024).

  • High-purity corticosterone for receptor binding assays: Corticosterone solutions are extensively used in receptor binding assays to understand corticosteroid receptor interactions. These studies are crucial for advancing knowledge in endocrinology biochemical studies, particularly in mapping corticosteroid pathways and their effects within the body (Xie et al., 2024).

  • Synthetic corticosterone solution for endocrine studies: Synthetic corticosterone is employed in clinical experimental setups to examine the endocrine system′s response under controlled conditions. This usage is particularly evident in studies focusing on the adaptation of the endocrine system to external stress factors and its impact on overall physiological health (Costa et al., 2024).

  • Liquid corticosterone for stress response research: Liquid formulations of corticosterone are pivotal in conducting stress response research, providing a consistent and measurable means of administering this hormone to study its acute and chronic effects on animal behavior and physiological responses (Ornelas et al., 2023).

  • Corticosterone reagent for glucocorticoid receptor experiments: As a reagent, corticosterone is integral to glucocorticoid receptor experiments, which are essential for understanding glucocorticoid receptor dynamics and their implications in various physiological processes, including immune response and metabolic regulation (Heraudeau et al., 2023).

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

T Shavlakadze et al.
American journal of physiology. Cell physiology, 305(1), C26-C35 (2013-04-19)
Circadian rhythms and metabolism are tightly integrated, and rhythmic expression of metabolic factors is common in homeostatic processes. We measured the temporal changes in the expression of myogenic regulatory factors and expression and activity level of molecules involved in protein
N E Ordian et al.
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 63(2), 280-289 (2013-07-23)
Anxious-depressive state was studied in experimental "stress-restress" model of posttraumatic stress disorder (PTSD) using adult rat males. Rat males were born by control females and whose mothers were under 60-minute immobilization stress since 15 until 19 days of pregnancy. Then
Krzysztof Gil et al.
Neuro endocrinology letters, 34(4), 314-321 (2013-06-28)
The brain and the gut communicate bi-directionally through the brain-gut axis. The key role in such interactions plays autonomic nervous system and its major component, the vagus nerve. There is growing evidence that vagus nerve stimulation (VNS) has a suppressive
L J F van de Ven et al.
Poultry science, 92(4), 1050-1061 (2013-03-09)
Little is known about physiological responses of early- versus late-hatching chicks to early posthatch conditions in broiler practice. We investigated effects of hatching time on perinatal broiler physiology in 2 hatching systems, differing in conditions: a conventional hatcher, where chicks
T V Shemenkova et al.
Bulletin of experimental biology and medicine, 154(4), 464-466 (2013-03-15)
ACTH1-24(1 mg/kg) administered to 5-7-day-old rats reduced their locomotor activity and did not alter blood levels of corticosterone. ACTH administration on postnatal days 12-14 increased corticosterone levels, but had no effect on locomotor activity. Thus, the behavioral effect of ACTH

Protocolos

The conversion of clinical methods to LC/MS/MS offers advantages; however, is accompanied by a few limitations, notably interference effects from the endogenous sample matrix.

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica