A-150

Aprobarbital solution

1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Fórmula empírica (Notação de Hill): C₁₀H₁₄N₂O₃
• Número CAS: 77-02-1
• Peso molecular: 210.23
• Número MDL: MFCD00057559
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: certified reference material
• Nível de qualidade: 300
• Formulário: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• embalagem: ampule of 1 mL
• fabricante/nome comercial: Cerilliant^®
• concentração: 1 mg/mL in methanol
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): forensics and toxicology
• Formato: single component solution
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C1C(C(C)C)(CC=C)C(NC(N1)=O)=O
• InChI: 1S/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15)
• chave InChI: UORJNBVJVRLXMQ-UHFFFAOYSA-N

Descrição

Descrição geral

Aprobarbital, also known as aprobarbitone, is sold as Oramon, Somnifaine and Allonal. Aprobarbital has sedative, hypnotic and anticonvulsant properties and was primarily used for the treatment of insomnia. This Snap-N-Spike Reference Solution is applicable for use in applications including clinical toxicology, medication monitoring, urine drug testing, and forensic analysis by LC-MS/MS or GC/MS.

Aplicação

• Rapid quantification of phenobarbital and barbital in human whole blood by liquid-liquid extraction combined with DART-orbitrap-HRMS: This method showcases the use of Aprobarbital-related compounds for forensic toxicology, highlighting its potential in precise legal and clinical diagnostics (Ke et al., 2023).


• Quantitative Determination of Methohexital in Human Whole Blood by Liquid Chromatography Tandem Mass Spectrometry: The study emphasizes the critical role of barbiturates like Aprobarbital in therapeutic monitoring, contributing to safer and more effective drug administration protocols (Zhang et al., 2021).


• Occurrence and fate of barbiturates in the aquatic environment: Research into environmental toxicology of compounds including Aprobarbital, providing insights into pollution control and drug lifecycle analysis (Peschka et al., 2006).


• Determinations of zidovudine/didanosine/nevirapine and zidovudine/didanosine/ritonavir in human serum by micellar electrokinetic chromatography: This analytical technique underlines the broader utility of methodologies applicable to barbiturate analysis like Aprobarbital in complex biological matrices (Fan and Stewart, 2002).


• Determination of lamivudine/stavudine/efavirenz in human serum using liquid chromatography/electrospray tandem mass spectrometry with ionization polarity switch: Demonstrates advanced analytical capabilities potentially extendable to Aprobarbital, enhancing drug monitoring and pharmacokinetic studies (Fan et al., 2002).

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H225,H301 + H311 + H331,H370
• Declarações de precaução: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órgãos-alvo: Eyes,Central nervous system
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 49.5 °F - closed cup
• Ponto de fulgor (°C): 9.7 °C - closed cup