857120P

14:0 Lyso PA

1-myristoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Sinônimo(s): 1-tetradecanoyl-sn-glycero-3-phosphate (sodium salt); PA(14:0/0:0); 14:0 LPA; 110677
• Fórmula empírica (Notação de Hill): C₁₇H₃₄O₇PNa
• Número CAS: 325465-45-0
• Peso molecular: 404.41
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Formulário: powder
• embalagem: pkg of 1 × 25 mg (857120P-25mg); pkg of 1 × 500 mg (857120P-500mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 857120P
• tipo de lipídio: phospholipids; cardiolipins
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C17H35O7P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(19)23-14-16(18)15-24-25(20,21)22;/h16,18H,2-15H2,1H3,(H2,20,21,22);/q;+1/p-1/t16-;/m1./s1
• chave InChI: HGENTPHNTSLRPB-PKLMIRHRSA-M

Descrição

Descrição geral

Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.

Aplicação

14:0 Lyso PA is suitable to use as internal standard to spike serum samples for the extraction of serum lipids. It is also suitable to use as standard lipids for extraction of lipids and for quality control in multiple reaction monitoring (MRM) assay.

Ações bioquímicas/fisiológicas

Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca²⁺ mobilization, neurotransmitter release and cell proliferation.

Embalagem

20 mL Clear Glass Screw Cap Vial (857120P-500mg)

5 mL Amber Glass Screw Cap Vial (857120P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids