850800C

20:4 PE

1,2-diarachidonoyl-sn-glycero-3-phosphoethanolamine, chloroform

• Sinônimo(s): 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine; DAPE; PE(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))
• Fórmula empírica (Notação de Hill): C₄₅H₇₄NO₈P
• Número CAS: 5634-86-6
• Peso molecular: 788.04
• Número MDL: MFCD00674343
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: liquid
• embalagem: pkg of 1 × 2.5 mL (850800C-25mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 850800C
• concentração: 10 mg/mL (850800C-25mg)
• tipo de lipídio: cardiolipins; phospholipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C45H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-44(47)51-41-43(42-53-55(49,50)52-40-39-46)54-45(48)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h11-14,17-20,23-26,29-32,43H,3-10,15-16,21-22,27-28,33-42,46H2,1-2H3,(H,49,50)/b13-11+,14-12+,19-17+,20-18+,25-23+,26-24+,31-29+,32-30+/t43-/m1/s1
• chave InChI: JTERLNYVBOZRHI-RIIGGKATSA-N

Descrição

Descrição geral

Phosphatidylethanolamine (PE) is a membrane phospholipid and the types depend on the combination of free fatty acids on the α and β position. 20:4 PE has arachidonic acid on the α and β positions.

Aplicação

20:4 PE has been used as an antigen in enzyme linked immunosorbent assay (ELISA) for detecting antiphosphatidylethanolamine (aPE) antibodies. It is suitable for use as an internal standard for electrospray ionization-mass spectrometry (ESI-MS), high performance liquid chromatography and in the preparation of lysophosphatidylethanolamine.

Ações bioquímicas/fisiológicas

Phosphatidylethanolamine (PE) is implicated in a numerous function like membrane fusion, cell cycle, autophagy, apoptosis, and cognitive function. 20:4 phosphatidylethanolamine (PE)/ DAPE induces cell death in malignant pleural mesothelioma (MPM) cells. DAPE enhances protein phosphatase 2A (PP2A) and protein tyrosine phosphatase 1B (PTB1B) activity.

Embalagem

5 mL Clear Glass Sealed Ampule (850800C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Declarações de precaução: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classificações de perigo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Órgãos-alvo: Central nervous system, Liver,Kidney
• Código de classe de armazenamento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): does not flash
• Ponto de fulgor (°C): does not flash