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Documentos Principais

850303P

Avanti

04:0 PC

1,2-dibutyryl-sn-glycero-3-phosphocholine, powder

Sinônimo(s):

PC(4:0/4:0)

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About This Item

Fórmula empírica (Notação de Hill):
C16H32NO8P
Número CAS:
Peso molecular:
397.40
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 25 mg (850303P-25mg)
pkg of 1 × 500 mg (850303P-500mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 850303P

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COC(CCC)=O)=O

InChI

1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1

chave InChI

QIJYAMAPPUXBSC-CQSZACIVSA-N

Descrição geral

04:0 PC is a water soluble phophatidylcholine analogue. Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicação

04:0 PC is suitable for use to evaluate its ability to form reverse micelles. It is also suitable for use as a phospholipid substrate to study the substrate specificity of glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP).

Ações bioquímicas/fisiológicas

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Embalagem

30 mL Amber Wide Mouth Bottle with Screw Cap (850303P-500mg)
5 mL Clear Glass Sealed Ampule (850303P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Role of reverse micelles on lipid oxidation in bulk oils: impact of phospholipids on antioxidant activity of alpha-tocopherol and Trolox
Chen B, et al.
Food & Function, 2(6), 302-309 (2011)
The Membranes of Cells (2016)
Characterization of glycerophosphoethanolamine ethanolaminephosphodiesterase from Streptomyces sanglieri
Mineta S, et al.
Journal of Bioscience and Bioengineering, 119(2), 123-130 (2015)
Mi-Kyung Oh et al.
Biochimica et biophysica acta, 1649(2), 146-153 (2003-07-25)
O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates (n=6, 8, and 10; CnPNC) were synthesized and characterized as inhibitors of phospholipase D (PLD) activity toward phosphatidylcholine presented as monomers, micelles, and bilayers. Detailed studies with recombinant Streptomyces chromofuscus PLD, a Ca(2+)-activated enzyme that does not show large
Integrative Medicine - E-Book (2017)

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