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840101C

Avanti

Egg PA

Avanti Research™ - A Croda Brand

Sinônimo(s):

L-α-phosphatidic acid (Egg, Chicken) (sodium salt)

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About This Item

Número CAS:
383907-53-7
Número MDL:
MFCD00672609
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

Formulário

liquid

embalagem

pkg of 1 × 2.5 mL (840101C-25mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand

concentração

10 mg/mL (840101C-25mg)

tipo de lipídio

phosphoglycerides

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)O

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

chave InChI

PPYXMAJBOKWTQX-RYRMQHSSSA-M

Descrição geral

Phosphatidic acid (PA) is synthesized by the action of phospholipase D (PLD) on glycerophospholipids and by phosphorylation of diacylglycerol (DAG) by DAG kinase.

Aplicação

Egg PA has been used in SEIPEN binding studies. It is suitable for use in the preparation of liposomes and to deduce different species of phosphatidic acid from egg by liquid chromatography-mass spectroscopy (LC-MS) and least squares spectral resolution (LSSR) analysis.

Ações bioquímicas/fisiológicas

Phosphatidic acid (PA) contributes to membrane biogenesis by involving in the synthesis of glycerophospholipids like phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol and phosphatidylserine. PA is implicated in cell signaling.

Embalagem

5 mL Clear Glass Sealed Ampule (840101C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system, Liver,Kidney

Classe de risco de água (WGK)

WGK 3

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Certificados de análise (COA)

Lot/Batch Number

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The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans
Klopfenstein DR and Vale RD
Molecular Biology of the Cell, 15(8), 3729-3739 (2004)
Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders (2015)
Extension of least squares spectral resolution algorithm to high-resolution lipidomics data
Zeng YX, et al.
Analytica Chimica Acta, 914(8), 35-46 (2016)
Human SEIPIN binds anionic phospholipids
Yan R, et al.
Developmental Cell, 47(2), 248-256 (2018)
Xianping Li et al.
Infection and immunity, 80(1), 429-440 (2011-11-16)
Aspergillus fumigatus is the most prevalent airborne fungal pathogen that induces serious infections in immunocompromised patients. Phospholipases are key enzymes in pathogenic fungi that cleave host phospholipids, resulting in membrane destabilization and host cell penetration. However, knowledge of the impact
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