810211C

C12-NBD Ceramide

Avanti Research^™ - A Croda Brand 810211C

• Sinônimo(s): N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine
• Fórmula empírica (Notação de Hill): C₃₆H₆₁N₅O₆
• Número CAS: 202850-01-9
• Peso molecular: 659.90
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: liquid
• embalagem: pkg of 1 × 1 mL (810211C-1mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 810211C
• concentração: 1 mg/mL (810211C-1mg)
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCCCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO
• InChI: 1S/C36H61N5O6/c1-2-3-4-5-6-7-8-9-10-12-15-18-21-24-33(43)31(29-42)38-34(44)25-22-19-16-13-11-14-17-20-23-28-37-30-26-27-32(41(45)46)36-35(30)39-47-40-36/h21,24,26-27,31,33,37,42-43H,2-20,22-23,25,28-29H2,1H3,(H,38,44)/b24-21+/t31-,33+/m0/s1
• chave InChI: SNOJCYCOPNIGIK-ULETYAGTSA-N

Descrição

Aplicação

C12-NBD ceramide is suitable for its use:

• as a substrate to measure the activity of acid, alkaline and neutral ceramidases
• in in vitro ceramidase activity assay
• in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)

Ações bioquímicas/fisiológicas

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Embalagem

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H302,H315,H319,H331,H336,H351,H361d,H372
• Declarações de precaução: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Classificações de perigo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Órgãos-alvo: Central nervous system
• Classe de risco de água (WGK): WGK 3