W518107

Sucrose acetate isobutyrate

• Sinônimo(s): SAIB
• Fórmula empírica (Notação de Hill): C₄₀H₆₂O₁₉
• Peso molecular: 846.91
• Número MDL: MFCD00041859
• Código UNSPSC: 12164502
• ID de substância PubChem: 24902076
• NACRES: NA.21

Propriedades

• fonte biológica: synthetic
• Nível de qualidade: 400
• grau: Kosher
• p.e.: 288 °C
• densidade: 1.146 g/mL at 25 °C
• aplicação(ões): flavors and fragrances
• Documentação: see Safety & Documentation for available documents
• alérgeno alimentar: no known allergens
• Organoléptico: odorless
• cadeia de caracteres SMILES: CC(C)C(=O)OC[C@]1(O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@H]2OC(=O)C(C)C
• InChI: 1S/C40H62O19/c1-18(2)33(43)51-17-40(32(57-38(48)23(11)12)29(54-35(45)20(5)6)27(58-40)16-50-25(14)42)59-39-31(56-37(47)22(9)10)30(55-36(46)21(7)8)28(53-34(44)19(3)4)26(52-39)15-49-24(13)41/h18-23,26-32,39H,15-17H2,1-14H3/t26-,27-,28-,29-,30+,31-,32+,39-,40+/m1/s1
• chave InChI: ZNEBZIJCDDCNRC-SWTLDUCYSA-N

Descrição

Aplicação

• An ultrasound-triggered injectable sodium alginate scaffold loaded with electrospun microspheres for on-demand drug delivery to accelerate bone defect regeneration.: This study highlights the use of Sucrose Acetate Isobutyrate (SAIB) in developing advanced drug delivery systems. SAIB is utilized to enhance the stability and controlled release properties of drug-loaded microspheres integrated into sodium alginate scaffolds, offering precise therapeutic management in bone regeneration applications (Yi Y et al., 2024).


• Sustained Release of Dexamethasone from 3D-Printed Scaffolds Modulates Macrophage Activation and Enhances Osteogenic Differentiation.: Incorporating SAIB into 3D-printed scaffolds has shown to effectively control the release rates of dexamethasone, a therapeutic agent, facilitating improved osteogenic differentiation and reduced inflammatory responses, crucial for bone healing and regeneration (Majrashi M et al., 2023).


• Application of Sucrose Acetate Isobutyrate in Development of Co-Amorphous Formulations of Tacrolimus for Bioavailability Enhancement.: Research demonstrates how SAIB can be used to develop co-amorphous drug formulations, specifically for tacrolimus, to enhance its bioavailability. This approach addresses significant challenges in drug solubility and stability, marking a significant advance in the formulation of poorly water-soluble drugs (Mohamed EM et al., 2023).

Exoneração de responsabilidade

For R&D or non-EU Food use. Not for retail sale.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves