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W296902

Sigma-Aldrich

Pyruvaldehyde solution

40 wt. % in H2O

Sinônimo(s):

Methylglyoxal solution, Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde

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About This Item

Fórmula linear:
CH3COCHO
Número CAS:
78-98-8
Peso molecular:
72.06
Número FEMA:
2969
Beilstein:
906750
Conselho da Europa nº:
105
Número MDL:
MFCD00006960
Código UNSPSC:
12164502
ID de substância PubChem:
24901425
Número de Flavis:
7.001
NACRES:
NA.21

fonte biológica

synthetic

grau

Halal

concentração

40 wt. % in H2O

índice de refração

n20/D 1.41

densidade

1.178 g/mL at 25 °C

aplicação(ões)

flavors and fragrances

Documentação

see Safety & Documentation for available documents

alérgeno alimentar

no known allergens

Organoléptico

caramel

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H]C(=O)C(C)=O

InChI

1S/C3H4O2/c1-3(5)2-4/h2H,1H3

chave InChI

AIJULSRZWUXGPQ-UHFFFAOYSA-N

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Descrição geral

Pyruvaldehyde solution may be used along with ammonium salts to prepare aqueous solutions that mimic atmospheric aerosol compositions to study the formation of absorbing secondary organic materials.

Exoneração de responsabilidade

For R&D or non-EU Food use. Not for retail sale.

Palavra indicadora

Danger

Frases de perigo

H290,H317,H318,H341

Classificações de perigo

Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
SHBP2833
STBK2288
STBJ3575
STBJ2962
STBJ1443

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

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Phenylglyoxal hydrate

Pyruvic acid 98%

Sigma-Aldrich

107360

Pyruvic acid

Aminoguanidine hydrochloride ≥98%

Sigma-Aldrich

396494

Aminoguanidine hydrochloride

L-2-Phosphoglyceric acid disodium salt hydrate ≥80% (CE)

Sigma-Aldrich

19710

L-2-Phosphoglyceric acid disodium salt hydrate

Glyoxal (40% solution in water) for synthesis

Sigma-Aldrich

8.20610

Glyoxal

DL-Glyceraldehyde ≥90% (GC)

Sigma-Aldrich

G5001

DL-Glyceraldehyde

DL-Glyceraldehyde 3-phosphate solution 45-55 mg/mL in H2O

Sigma-Aldrich

G5251

DL-Glyceraldehyde 3-phosphate solution

Dihydroxyacetone for synthesis

Sigma-Aldrich

8.20482

Dihydroxyacetone

Secondary organic material formed by methylglyoxal in aqueous aerosol mimics.
Sareen N, et al.
Atmospheric Chemistry and Physics, 10(3) (2010)
T W Lo et al.
Biochemical pharmacology, 48(10), 1865-1870 (1994-11-16)
Increased formation of methylglyoxal in clinical diabetes mellitus and metabolism by the glyoxalase system has been linked to the development of clinical complications of diabetes: retinopathy, neuropathy and nephropathy. Aminoguanidine has been proposed as a prophylactic agent for preventive therapy
Georg T Wondrak et al.
Biochemical pharmacology, 63(3), 361-373 (2002-02-21)
Tissue deterioration and aging have long been associated with the accumulation of chemically induced protein and DNA damage. Reactive oxygen species (ROS) and reactive carbonyl species (RCS), especially alpha-dicarbonyl compounds, are key mediators of damage caused by oxidative stress, glycation
Wei-Hsuan Hsu et al.
Toxicology and applied pharmacology, 272(3), 842-851 (2013-08-21)
Methylglyoxal (MG) is a toxic-glucose metabolite and a major precursor of advanced glycation endproducts (AGEs). MG has been reported to result in inflammation by activating receptor for AGEs (RAGE). We recently found that Monascus-fermented metabolite monascin acts as a novel
Paul J Beisswenger et al.
Diabetes, 54(11), 3274-3281 (2005-10-27)
Dicarbonyl and oxidative stress may play important roles in the development of diabetes complications, and their response to hyperglycemia could determine individual susceptibility to diabetic nephropathy. This study examines the relationship of methylglyoxal, 3-deoxyglucosone (3DG), and oxidative stress levels to
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