QBD10211

m-dPEG^®₄-NHS ester

• Sinônimo(s): 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13-tetraoxatetradecanoate, Polyethylene glycol, Triethylene glycol methyl ether 2-(succinimidyloxycarbonyl)ethyl ether
• Fórmula empírica (Notação de Hill): C₁₄H₂₃NO₈
• Número CAS: 622405-78-1
• Peso molecular: 333.33
• Número MDL: MFCD11041112
• Código UNSPSC: 12352108
• ID de substância PubChem: 329823894
• NACRES: NA.22

Propriedades

• Ensaio: >90%
• Formulário: solid or viscous liquid
• adequação da reação: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• arquitetura do polímero: shape: linear; functionality: monofunctional
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C1CCC(N1OC(CCOCCOCCOCCOC)=O)=O
• InChI: 1S/C14H23NO8/c1-19-6-7-21-10-11-22-9-8-20-5-4-14(18)23-15-12(16)2-3-13(15)17/h2-11H2,1H3
• chave InChI: MAYFFZZPEREGBQ-UHFFFAOYSA-N

Descrição

Características e benefícios

The m-dPEG^®₄-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₄-NHS (N-hydroxysuccinimide) ester reacts with amines.

Informações legais

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable