QBD10260

m-dPEG^®₈-NHS ester

• Sinônimo(s): 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid succinimidyl ester, 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25-octaoxahexacosanoate, Polyethylene glycol
• Fórmula empírica (Notação de Hill): C₂₂H₃₉NO₁₂
• Número CAS: 756525-90-3
• Peso molecular: 509.54
• Número MDL: MFCD13184969
• Código UNSPSC: 12352108
• ID de substância PubChem: 329823901
• NACRES: NA.22

Propriedades

• Ensaio: >90%
• forma: solid or viscous liquid
• adequação da reação: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• arquitetura do polímero: shape: linear; functionality: monofunctional
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOC)ON1C(CCC1=O)=O
• InChI: 1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
• chave InChI: IBZNTYBFTKFSMU-UHFFFAOYSA-N

Descrição

Características e benefícios

The m-dPEG^®₈-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₈-NHS ester reacts with amines.

Informações legais

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable