G11950

Guanine

98%

• Sinônimo(s): 2-Amino-1,7-dihydro-6H-purin-6-one, 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine
• Fórmula empírica (Notação de Hill): C₅H₅N₅O
• Número CAS: 73-40-5
• Peso molecular: 151.13
• Beilstein: 9680
• Número CE: 200-799-8
• Número MDL: MFCD00071533
• Código UNSPSC: 12352005
• ID de substância PubChem: 24895050
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Ensaio: 98%
• pf: >300 °C (lit.)
• solubilidade: hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green
• cadeia de caracteres SMILES: NC1=Nc2[nH]cnc2C(=O)N1
• InChI: 1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• chave InChI: UYTPUPDQBNUYGX-UHFFFAOYSA-N

Descrição

Descrição geral

Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine.

Aplicação

Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves