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79229

Sigma-Aldrich

N-Boc-1,6-hexanediamine

≥98.0% (NT)

Sinônimo(s):

N-Boc-1,6-diaminohexane, tert-Butyl-N-(6-aminohexyl)carbamate

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About This Item

Fórmula empírica (Notação de Hill):
C11H24N2O2
Número CAS:
51857-17-1
Peso molecular:
216.32
Beilstein:
2219107
Número MDL:
MFCD00671489
Código UNSPSC:
12352116
ID de substância PubChem:
57652779
NACRES:
NA.22

Ensaio

≥98.0% (NT)

forma

liquid

adequação da reação

reagent type: cross-linking reagent

índice de refração

n20/D 1.462

densidade

0.965 g/mL at 20 °C (lit.)

grupo funcional

Boc
amine

cadeia de caracteres SMILES

NCCCCCCNC(OC(C)(C)C)=O

InChI

1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)

chave InChI

RVZPDKXEHIRFPM-UHFFFAOYSA-N

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Aplicação

N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C6-spacer) to synthesize:
  • Biodegradable poly(disulfide amine)s for gene delivery.
  • A multifunctional dendrimer for theranostics.
  • Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
  • Self-assembled monolayers (SAMs) that resist adsorption of proteins.
  • [N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.
Reagent for the introduction of a C6-spacer.

Pictogramas

Corrosion
GHS05

Palavra indicadora

Danger

Frases de perigo

H314

Classificações de perigo

Eye Dam. 1 - Skin Corr. 1B

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

257.0 °F - closed cup

Ponto de fulgor (°C)

125 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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A label-free electrochemical immunosensor for direct, signal-on and sensitive pesticide detection.
Tran HV, et al.
Biosensors And Bioelectronics, 31(1), 62-68 (2012)
Haonan Xing et al.
Colloids and surfaces. B, Biointerfaces, 182, 110355-110355 (2019-07-16)
Inspired by the excellent membrane affinity of antimicrobial polymers, we synthesized a novel biodegradable poly(amino amine) polymer with pendent side chains that mimic the widely used biocide polyhexamethylene biguanide (PHMB) for gene delivery. Michael addition polymerization was utilized to form
Construction of a well-defined multifunctional dendrimer for theranostics.
Ornelas C, et al.
Organic Letters, 13(5), 976-979 (2011)
Yan Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 328, 970-984 (2020-09-15)
To avoid poly(ethylene glycol)-related issues of nanomedicines such as accelerated blood clearance, fully N-2-hydroxypropyl methacrylamide (HPMAm)-based polymeric micelles decorated with biotin for drug delivery were designed. To this end, a biotin-functionalized chain transfer agent (CTA), 4-cyano-4-[(dodecylsulfanylthiocarbonyl)-sulfanyl]pentanoic acid (biotin-CDTPA), was synthesized
Preparation of mixed self-assembled monolayers (SAMs) that resist adsorption of proteins using the reaction of amines with a SAM that presents interchain carboxylic anhydride groups.
Chapman R G, et al.
Langmuir, 16(17), 6927-6936 (2000)
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