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Documentos Principais

687537

Sigma-Aldrich

Poly(ethylene glycol) dimethacrylate

average MN 6,000, cross-linking reagent polymerization reactions, methacrylate, 1000 ppm 4-methoxyphenol as inhibitor

Sinônimo(s):

Polyethylene glycol, PEG dimethacrylate

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About This Item

Fórmula linear:
C3H5C(O)(OCH2CH2)nOC(O)C3H5
Número CAS:
Número MDL:
Código UNSPSC:
12162002
NACRES:
NA.23

Nome do produto

Poly(ethylene glycol) dimethacrylate, average Mn 6,000, contains 1000 ppm 4-methoxyphenol as inhibitor

Formulário

powder

peso molecular

average Mn 6,000

contém

1000 ppm 4-methoxyphenol as inhibitor

adequação da reação

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

p.e.

>200 °C/2 mmHg (lit.)

temperatura de transição

Tm 50.2-53.7 °C

Mw/Mn

<1.2

Ω-final

methacrylate

α-final

methacrylate

arquitetura do polímero

shape: linear
functionality: homobifunctional

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OCCO.CC(=C)C(O)=O

InChI

1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3

chave InChI

STVZJERGLQHEKB-UHFFFAOYSA-N

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1


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Hailuo Fu et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2245-2250 (2013-03-19)
Implants that simultaneously function as an osteoconductive matrix and as a device for local drug or growth factor delivery could provide an attractive system for bone regeneration. In our previous work, we prepared hollow hydroxyapatite (abbreviated HA) microspheres with a
Sophia W Liao et al.
Biomaterials, 34(16), 3984-3991 (2013-03-08)
Islet transplantation offers a promising treatment for type 1 diabetes (T1D). However, a major hurdle in this treatment is the rapid loss of functional islets during culture and after transplantation. The liver site, currently utilized for transplantation, is suboptimal for
Pelagie M Favi et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1935-1944 (2013-03-19)
The culture of multipotent mesenchymal stem cells on natural biopolymers holds great promise for treatments of connective tissue disorders such as osteoarthritis. The safety and performance of such therapies relies on the systematic in vitro evaluation of the developed stem
C Aulin et al.
Laboratory animals, 47(1), 58-65 (2013-03-08)
Articular cartilage has a limited capacity for self-repair in adult humans, and methods used to stimulate regeneration often result in re-growth of fibrous cartilage, which has lower durability. No current treatment option can provide complete repair. The possibility of growth
Xuan Mu et al.
Lab on a chip, 13(8), 1612-1618 (2013-03-05)
Engineering functional vascular networks in vitro is critical for tissue engineering and a variety of applications. There is still a general lack of straightforward approaches for recapitulating specific structures and functions of vasculature. This report describes a microfluidic method that

Artigos

Patterning of PEG-based Hydrogels - Engineering Spatial Complexity

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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