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409537

Sigma-Aldrich

Poly(ethylene glycol) methacrylate

average Mn 360, methacrylate, 500-800 ppm MEHQ as inhibitor

Sinônimo(s):

Ethoxylated 2-hydroxyethyl methacrylate, PEGMA, Poly(ethylene oxide) monomethacrylate, Polyethylene glycol

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About This Item

Fórmula linear:
H2C=C(CH3)CO(OCH2CH2)nOH
Número CAS:
25736-86-1
Número MDL:
MFCD00081879
Código UNSPSC:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) methacrylate, average Mn 360, contains 500-800 ppm MEHQ as inhibitor

forma

liquid

peso molecular

average Mn 360

contém

500-800 ppm MEHQ as inhibitor

adequação da reação

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

índice de refração

n20/D 1.464

densidade

1.105 g/mL at 25 °C

Ω-final

hydroxyl

α-final

methacrylate

arquitetura do polímero

shape: linear
functionality: heterobifunctional

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

chave InChI

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Descrição geral

Polyethylene glycol (PEG) is a suitable material for biological applications since it does not trigger an immune response. It can by synthesized by anionic ring opening polymerization of ethylene oxide with a range of end groups (such as methacrylate: PEGMA) attached. PEG is a hydrophilic polymer that can form hydrogels when cross linked into networks. Acrylate and methacrylate chain ends undergo chain polymerization to from PEGMA hydrogels.

Aplicação

PEGMA can beused as a monomer to synthesize:
  • Degradable microspheres using asuspension polymerization process. The amphiphilic nature of PEGMA allows performingthe polymerization by direct oil in the water suspension process.
  • Polymeric chelating beads for the effectiveremoval of heavy metals from aqueous solutions.
It can also be used to synthesize micro or nanoparticles-basedchitosan /PEGMA composite by Michael addition reaction. The PEGMA graftingimproves the solubility of chitosan in aqueous media. These particles can beused as carriers in the ophthalmic drug delivery system.

forma física

Monomethacrylate functionalized

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315

Classificações de perigo

Skin Irrit. 2

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

235.4 °F - closed cup

Ponto de fulgor (°C)

113 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Mir Mukkaram Ali;
Macromolecules, 37, 5219-5227 (2004)
Biofouling-resistance expanded poly (tetrafluoroethylene) membrane with a hydrogel-like layer of surface-immobilized poly (ethylene glycol) methacrylate for human plasma protein repulsions.
Chang Y, et al.
Journal of Membrane Science, 323(1), 77-84 (2008)

Artigos

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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