About This Item
Fórmula empírica (Notação de Hill):
C17H16O6
Número CAS:
Peso molecular:
316.31
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
Produtos recomendados
Ensaio
97%
Formulário
solid
pf
310 °C (lit.)
grupo funcional
carboxylic acid
cadeia de caracteres SMILES
OC(=O)c1ccc(OCCCOc2ccc(cc2)C(O)=O)cc1
InChI
1S/C17H16O6/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H,18,19)(H,20,21)
chave InChI
VBISQLWPGDULSX-UHFFFAOYSA-N
Categorias relacionadas
Aplicação
Building block for polyanhydrides, a class of bioerodible polymer with drug delivery applications.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Aquatic Acute 1 - Skin Sens. 1
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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A J Domb et al.
Biomaterials, 15(9), 681-688 (1994-07-01)
The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, and the other co-polymer with [14C]CPP and unlabelled SA.
Xiaohua Liu et al.
Biomaterials, 28(28), 4124-4131 (2007-06-20)
Intermittent (pulsatile) administration of parathyroid hormone (PTH) is known to improve bone micro-architecture, mineral density and strength. Therefore, daily injection of PTH has been clinically used for the treatment of osteoporosis. However, this regimen of administration is not convenient and
Moon Suk Kim et al.
Bio-medical materials and engineering, 15(3), 229-238 (2005-05-25)
p-Carboxyphenoxy propane (CPP) prepolymer consisting of 4 units and sebacic acid (SA) prepolymer consisting of about 10 units were synthesized by reacting CPP and SA in the presence of excess acetic anhydride, respectively. Polyanhydride, poly(CPP-SA) copolymers were copolymerized by a
A D'Emanuele et al.
Pharmaceutical research, 9(10), 1279-1283 (1992-10-01)
We report a study of the effects of polymer molecular weight on the erosion of polyanhydride copolymer matrices composed of 1,3-bis(p-carboxyphenoxy)-propane (CPP) and sebacic acid (SA) in aqueous solution. The erosion profile characteristically displays an induction period during which the
Sijian Hou et al.
Macromolecular bioscience, 7(5), 620-628 (2007-04-26)
To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis(p-carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with increasing PEG content.
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