323322

Trimethylphosphine

97%

• Sinônimo(s): PMe₃
• Fórmula linear: (CH₃)₃P
• Número CAS: 594-09-2
• Peso molecular: 76.08
• Beilstein: 969138
• Número CE: 209-823-1
• Número MDL: MFCD00008510
• Código UNSPSC: 12352128
• ID de substância PubChem: 24859357
• NACRES: NA.22

Propriedades

• pressão de vapor: 7.24 psi ( 20 °C)
• Ensaio: 97%
• Formulário: liquid
• adequação da reação: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand; reaction type: Mitsunobu Reaction; reagent type: ligand; reaction type: Wittig Reaction
• índice de refração: n20/D 1.428 (lit.)
• p.e.: 38-40 °C (lit.)
• pf: −86 °C (lit.)
• densidade: 0.738 g/mL at 20 °C (lit.)
• grupo funcional: phosphine
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CP(C)C
• InChI: 1S/C3H9P/c1-4(2)3/h1-3H3
• chave InChI: YWWDBCBWQNCYNR-UHFFFAOYSA-N

Descrição

Aplicação

Trimethylphosphine (PMe₃) is an electron-rich phosphine ligand used as a reagent in Mitsunobu reaction.
It can be used:

• In transformation of azides into carbamates; aziridines to azidoalcohols; and ketoximes to ketones with 2,2′-dipyridyl diselenide.
• In Aza-Wittig reaction;, C-H bond activation of imines; cross-coupling reactions.
• In the preparation of (cyanomethylene) trimethylphosphorane (CMMP) which is used as a reagent in Mitsunobu type reaction.
• As a reagent in the synthesis of ruthenium trimethylphosphine complexes, which in turn are used as catalysts for hydrogenation of CO₂ to formic acid.

Informações de segurança

• Pictogramas: GHS02,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H225,H315,H319,H335
• Declarações de precaução: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): -2.2 °F - closed cup
• Ponto de fulgor (°C): -19 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves