317500

(1S,2R)-(+)-Norephedrine

98%

• Sinônimo(s): (1S,2R)-2-Amino-1-phenyl-1-propanol, erythro-α-(1-aminoethyl)benzyl alcohol, D-(+)-Norephedrine, Phenylpropanolamine
• Fórmula linear: C₆H₅CH(OH)CH(CH₃)NH₂
• Número CAS: 37577-28-9
• Peso molecular: 151.21
• Beilstein: 2802896
• Número MDL: MFCD00064411
• Código UNSPSC: 12352116
• ID de substância PubChem: 24859081
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Ensaio: 98%
• forma: solid
• atividade óptica: [α]20/D +40°, c = 7 in 1 M HCl
• pf: 51-54 °C (lit.)
• grupo funcional: amine; hydroxyl; phenyl
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: C[C@@H](N)[C@@H](O)c1ccccc1
• InChI: 1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1
• chave InChI: DLNKOYKMWOXYQA-VXNVDRBHSA-N

Descrição

Descrição geral

(1S,2R)-(+)-Norephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.

Aplicação

(1S,2R)-(+)-Norephedrine may be used in the preparation of dendritic ligands, which on combining with Ru(II) complexes form efficient asymmetric transfer hydrogenation catalysts. It may also be used in the preparation of N-((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)furan-2-carboxamide. This chiral amide can efficiently catalyze the enantioselective ethylation of aromatic and heteroaromatic aldehydes to secondary alcohols in the absence of titanium tetraisopropoxide as promotor.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302,H315,H319,H335
• Declarações de precaução: P261 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 235.4 °F - closed cup
• Ponto de fulgor (°C): 113 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves