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270873

Sigma-Aldrich

2-Hydroxyquinoline

98%

Sinônimo(s):

2-Quinolinol, Carbostyril

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About This Item

Fórmula empírica (Notação de Hill):
C9H7NO
Número CAS:
59-31-4
Peso molecular:
145.16
Número CE:
200-420-6
Número MDL:
MFCD00006743
Código UNSPSC:
12352100
ID de substância PubChem:
24856409
NACRES:
NA.22

Nível de qualidade

100

Ensaio

98%

Formulário

crystals

pf

198-199 °C (lit.)

solubilidade

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

cadeia de caracteres SMILES

Oc1ccc2ccccc2n1

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

chave InChI

LISFMEBWQUVKPJ-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

Aplicação

2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity.

Pictogramas

CorrosionExclamation mark
GHS05,GHS07

Palavra indicadora

Danger

Frases de perigo

H302,H315,H318,H335

Classificações de perigo

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
15529BQ
13831JZ
04824PT
18904PS
17608KO

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Hui-Chung Tai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(34), 10630-10642 (2012-07-19)
Diazido Pt(IV) complexes are inert stable prodrugs that can be photoactivated to produce Pt(II) species with promising anticancer activity. Our studies of the photochemistry of Pt(IV) complexes, [Pt(X)(2) (Y)(2) (Z)(2) ](0/-1) (X=N-ligands (NH(3) , pyridine, etc.)/S(CH(3) )(2) /H(-) , Y=(pseudo)halogen
Kaitlyn M Ferguson et al.
Frontiers in microbiology, 9, 2190-2190 (2018-10-05)
Objective: The intestinal concentrations of antimicrobial drugs that select for resistance in fecal bacteria of cattle are poorly understood. Our objective was to associate active drug concentrations in the intestine of steers with changes in the resistance profile and composition
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Cryptosporidium is a genus of single celled parasites capable of infecting a wide range of animals including humans. Cryptosporidium species are members of the phylum apicomplexa, which includes well-known genera such as Plasmodium and Toxoplasma. Cryptosporidium parasites cause a severe
Shirin Biglari et al.
Microbial drug resistance (Larchmont, N.Y.), 23(5), 545-555 (2016-11-18)
Multidrug-resistant (MDR) Acinetobacter baumannii has increasingly emerged as an important nosocomial pathogen. The aim of this study was to determine the resistance profiles and genetic diversity in A. baumannii clinical isolates in a tertiary medical center in Malaysia. The minimum
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Journal of nanobiotechnology, 18(1), 51-51 (2020-03-20)
The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequently, preventing bacterial colonization of implanted prosthetic meshes is of major clinical relevance for patients undergoing
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