247383

Boron tribromide dimethyl sulfide complex solution

1.0 M in methylene chloride

• Sinônimo(s): Dimethyl sulfide-tribromoborane, Tribromoborane-methyl sulfide
• Fórmula linear: (CH₃)₂S·BBr₃
• Número CAS: 29957-59-3
• Peso molecular: 312.66
• Número MDL: MFCD00043296
• Código UNSPSC: 12352101
• ID de substância PubChem: 24854866
• NACRES: NA.22

Propriedades

• Formulário: liquid
• concentração: 1.0 M in methylene chloride
• densidade: 1.456 g/mL at 25 °C
• grupo funcional: thioether
• cadeia de caracteres SMILES: C[S+](C)[B-](Br)(Br)Br
• InChI: 1S/C2H6BBr3S/c1-7(2)3(4,5)6/h1-2H3
• chave InChI: NCVLHAUANAMSTL-UHFFFAOYSA-N

Descrição

Aplicação

Boron tribromide dimethyl sulfide complex (BBr₃S(CH₃)₂) can be used as a reagent:

• To prepare demethylated products from aryl methyl ethers by deprotection of methyl groups.
• To hydrolyze 1,3-methylenedioxole ring compounds to 1,2-dihydroxy compounds.
• To prepare benzyl S,S′-diphenyl acetal by reacting with phenylacetic acid and thexylphenylthioborane.
• To synthesize Baylis−Hillman adducts and α-halomethyl enones by the reaction between aldehydes and 3-buten-2-one.

Reactant for preparation of:

• Precursor of HIV protease inhibitor KNI 764 using cation-exchange resin mediated Mannich reaction

Reagent for:

• Baylis-Hillman reactions

Informações de segurança

• Pictogramas: GHS08,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H314,H336,H351
• Declarações de precaução: P202 - P261 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Órgãos-alvo: Central nervous system
• Perigos de suplementos: EUH014
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable