246263

Indole-4-carboxylic acid

98%

• Sinônimo(s): 4-Carboxyindole
• Fórmula empírica (Notação de Hill): C₉H₇NO₂
• Número CAS: 2124-55-2
• Peso molecular: 161.16
• Número MDL: MFCD00009739
• Código UNSPSC: 12352100
• ID de substância PubChem: 24854799
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 98%
• Formulário: powder
• pf: 213-214 °C (lit.)
• cadeia de caracteres SMILES: OC(=O)c1cccc2[nH]ccc12
• InChI: 1S/C9H7NO2/c11-9(12)7-2-1-3-8-6(7)4-5-10-8/h1-5,10H,(H,11,12)
• chave InChI: ROGHUJUFCRFUSO-UHFFFAOYSA-N

Descrição

Aplicação

• Reactant for preparation of substituted indole derivatives as histamine H3 antagonists
• Reactant for preparation of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1
• Reactant for preparation of inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of pyridinyl carboxylates as SARS-CoV 3CL proinhibitors
• Reactant for preparation of substituted bipiperidinylmethyl amides as CCR3 membrane binding ligands
• Reactant for preparation of indole amide hydroxamic acids as potent inhibitors of histone deacetylases
• Reactant for preparation of 2-[[[4′-chloro-[1,1-biphenyl]-4-yl]thio]methyl]-N-hydroxybutanamide derivatives as specific metalloproteinase

tert-butyl esters of indole and pyrrolecarboylic acids are readily prepared by direct treatment with N,N-dimethylformamide di-tert-butyl acetal (Cat. No. 395005).

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves