SCN2A
sodium channel, voltage-gated, type II, alpha subunit
Sinônimos:
BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2
Espécies:
Human SCN2A (6326), chicken SCN2A (395945), dog SCN2A (478773), Horse SCN2A (100051816), domestic cat SCN2A (101080472), domestic guinea pig Scn2a (100716680), naked mole-rat Scn2a (101715020), cow SCN2A (539718), sheep SCN2A (101103126)
ID UniProtKB:
ID do gene:
- Human(6326) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
- chicken(395945) sodium channel, voltage-gated, type II, alpha subunit
- dog(478773) sodium channel, voltage-gated, type II, alpha subunit
- Horse(100051816) sodium channel, voltage-gated, type II, alpha subunit
- domestic cat(101080472) sodium channel, voltage-gated, type II, alpha subunit
- domestic guinea pig(100716680) sodium channel, voltage-gated, type II, alpha subunit
- naked mole-rat(101715020) sodium channel, voltage-gated, type II, alpha subunit
- cow(539718) sodium channel, voltage-gated, type II, alpha subunit
- sheep(101103126) sodium channel, voltage-gated, type II, alpha subunit
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Small Molecule - Antagonist
Product Number
Descrição
Espécies
Antibodies
Product Number
Descrição
Reatividade de espécies
Aplicação
Anti-SCN2A Antibody, clone 5H10.2, clone 5H10.2, from mouse,
Reatividade de espécies
human
Aplicação
western blot
Anti-SODIUM CHANNEL-PAN antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type II, Chemicon®, from rabbit,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Reatividade de espécies
mammals
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Product Number
Descrição
Espécies
esiRNA
Product Number
Descrição
Espécies