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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Sinônimos:
C-Kit, CD117, PBT, SCFR
Espécies:
Human KIT (3815), Mouse Kit (16590), Rat Kit (64030), chicken KIT (378783), domestic cat KIT (493766), cow KIT (280832), Horse KIT (100009704), dog KIT (403811), Goat KIT (100861386), sheep KIT (780504) ...Mais
ID UniProtKB:
P10721, B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99
ID do gene:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Custom & Knockdown Gene Products

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ELISA

Número do produto
Descrição
Espécies
RAB0731
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Espécies
human
RAB0992
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
07-806
Anti-phospho-c-Kit (Tyr568/Tyr570) Antibody, Upstate®, from rabbit,
Reatividade de espécies
human
Aplicação
western blot
SAB4501648
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
CBL1360
Anti-CD117 Antibody, clone ACK2, clone ACK2, Chemicon®, from rat,
Reatividade de espécies
mouse
Aplicação
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA004471
Anti-KIT antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
SAB4700750
Monoclonal Anti-CD117 antibody produced in mouse, clone 104D2, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
bovine, human, nonhuman primates
Aplicação
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
PZ0012
Sunitinib malate, ≥98% (HPLC),
Espécies
human
CDS023580
Pazopanib, ,
Espécies
human
SML2589
Dasatinib, ≥98% (HPLC),
Espécies
human
CDS023389
Dasatinib, ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
14-559-M
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
Espécies
human
14-611-M
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
Espécies
human
SRP0342
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Espécies
human
SRP5299
c-KIT (D820E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human
SRP5308
c-KIT (T670E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU049661
MISSION® esiRNA, targeting mouse Kit,
Espécies
mouse
EHU000841
MISSION® esiRNA, targeting human KIT,
Espécies
human