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Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Sinônimos:
DNMT3A2, M.HsaIIIA
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
bovine, human, mouse, rat
Aplicação
ELISA
western blot
Anti-DNMT3A2 Antibody, from rabbit,
Reatividade de espécies
human
Aplicação
ELISA
immunocytochemistry

western blot
Anti- DNMT3A antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-DNMT3A antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
5-Aza-2′-deoxycytidine, ≥97%,
Espécies
human
5-Azacytidine, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Espécies
human
Azacitidine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
5-Azacytidine, ≥98% (HPLC),
Espécies
human

Proteins

Número do produto
Descrição
Espécies
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Espécies
human
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human DNMT3A,
Espécies
human
MISSION® esiRNA, targeting mouse Dnmt3a,
Espécies
mouse