Accéder au contenu
Merck
Toutes les photos(1)

Principaux documents

Voir toute la documentation

914460

Sigma-Aldrich

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride

≥95%

Synonyme(s) :

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride, N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide hydrochloride, N-{2-[2-(2- Aminoethoxy)ethoxy]ethoxy}biotinamide hydrochloride, Amine-terminated biotin linker, Biotin-DOOA HCl, Biotinylation reagent

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill) :
C16H31ClN4O4S
Numéro CAS:
862373-14-6
Poids moléculaire :
410.96
Numéro MDL:
MFCD13185031
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.22

Niveau de qualité

100

Essai

≥95%

Forme

powder

Température de stockage

2-8°C

Chaîne SMILES 

S1[C@H]([C@H]2NC(=O)N[C@H]2C1)CCCCC(=O)NCCOCCOCCN.Cl

InChI

1S/C16H30N4O4S.ClH/c17-5-7-23-9-10-24-8-6-18-14(21)4-2-1-3-13-15-12(11-25-13)19-16(22)20-15;/h12-13,15H,1-11,17H2,(H,18,21)(H2,19,20,22);1H/t12-,13-,15-;/m0./s1

Clé InChI

UNQYTGLJZONNBD-HZPCBCDKSA-N

Application

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Autres remarques

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell Surface Anchoring of Multivalent Antibody-Recruiting Polymers

Caged Cyclopropenes with Improved Tetrazine Ligation Kinetics

A Unified Framework for the Incorporation of Bioorthogonal Compound Exposure Probes within Biological Compartments

A Chemical Probe for Protein Crotonylation

One-Step Selective Exoenzymatic Labeling (SEEL) Strategy for the Biotinylation and Identification of Glycoproteins of Living Cells

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

T2879

Tyramine hydrochloride, ≥98%

H1759

(+)-Biotin N-hydroxysuccinimide ester, ≥98% (HPLC), powder

B7639

(+)-Biotin hydrazide, ≥97% (TLC), powder

B5768

Biotin 4-amidobenzoic acid sodium salt, ≥95%

14400

Biotine, ≥99.0% (T)

861650

(+)-Biotin 4-nitrophenyl ester, 98%

B2059

Biotin Polyethyleneoxide Iodoacetamide

764213

Biotin-PEG4-alkyne, for copper catalyzed click labeling

QBD10196

Biotin-dPEG®11-NH2

QBD10826

Biotin-dPEG®7-NH2

SML2135

Biotinyl tyramide, ≥97% (HPLC)

914916

Biotin-SS-tyramide, ≥95%

914134

5-(Biotinamido)pentylamine TFA Salt, ≥95%

914924

3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid, ≥95%

913669

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

Si vous avez besoin d'assistance, veuillez contacter Service Clients

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Zhiyuan Fang et al.
Chemical communications (Cambridge, England), 49(55), 6164-6166 (2013-06-04)
A direct ELISA was established for the fast detection of semicarbazide (SEM) using a novel biotin derivative. Without a tedious extraction procedure, as low as 0.07 μg L(-1) of SEM could be detected reproducibly. This assay has better recovery and
Benjamin Spangler et al.
ACS chemical biology, 14(4), 725-734 (2019-03-26)
Compartmentalization is a crucial facet of many biological systems, and key aspects of cellular processes rely on spatial segregation within the cell. While many drug targets reside in specific intracellular compartments, the tools available for assessing compound exposure are generally
Dilini N Kekulandara et al.
Biochemistry, 57(5), 772-780 (2017-12-21)
Thioredoxin 1 (Trx1) and glutaredoxin 1 (Grx1) are two ubiquitous redox enzymes that are central for redox homeostasis but also are implicated in many other processes, including stress sensing, inflammation, and apoptosis. In addition to their enzymatic redox activity, a
Sebastian Pomplun et al.
Angewandte Chemie (International ed. in English), 58(11), 3542-3547 (2019-01-18)
We discovered N-pyrrolyl alanine derivatives as efficient reagents for the fast and selective Pictet-Spengler reaction with aldehyde-containing biomolecules. Other aldehyde-labeling methods described so far have several drawbacks, like hydrolytic instability, slow reaction kinetics or not readily available labeling reagents. Pictet-Spengler
Yali Yuan et al.
Chemical communications (Cambridge, England), 54(80), 11352-11355 (2018-09-25)
We have developed highly fluorescent, monolithic colloidal CdSe seeded CdS nanorod clusters comprising thousands of nanorods. Their use in the sandwich assay detection of a model protein yields a thousand-fold improvement in the detection limit compared to individual nanorods, making
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique