SML2843

NS3623

≥98% (HPLC)

• Synonym(e): 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea, N-[4-Bromo-2-(2H-tetrazol-5-yl)phenyl]-N′-[3-(trifluoromethyl)phenyl]urea, NS 3623
• Empirische Formel (Hill-System): C₁₅H₁₀BrF₃N₆O
• CAS-Nummer: 343630-41-1
• Molekulargewicht: 427.18
• MDL-Nummer: MFCD22683830
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: FC(F)(F)c1cc(ccc1)NC(=O)Nc2c(cc(cc2)Br)c3[nH]nnn3
• InChI: 1S/C15H10BrF3N6O/c16-9-4-5-12(11(7-9)13-22-24-25-23-13)21-14(26)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H2,20,21,26)(H,22,23,24,25)
• InChIKey: JXPULDIATMTIIN-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

NS3623 is a potent and selective activator of KV11.1 (hERG) and KV4.3 channels. It activates the IKr and Ito currents and exhibits antiarrhythmic activity. NS3623 may also act as a partial blocker of KV11.1 channels.

potent and selective activator of KV11.1 (hERG) and KV4.3 channels; antiarrhythmic

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable