SML1606

Oseltamivirphosphat

≥98% (HPLC)

• Synonym(e): (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexen-1-carbonsäure-ethylester -phosphat (Salz)
• Empirische Formel (Hill-System): C₁₆H₂₈N₂O₄ ·H₃PO₄
• CAS-Nummer: 204255-11-8
• Molekulargewicht: 410.40
• MDL-Nummer: MFCD08059548
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825492
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D -26 to -36°, c = 1 in H₂O
• Farbe: white to beige
• Löslichkeit: H₂O: 30 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: OP(O)(O)=O.CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
• InChI: 1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/m0./s1
• InChIKey: PGZUMBJQJWIWGJ-ONAKXNSWSA-N

Beschreibung

Biochem./physiol. Wirkung

Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. Oseltamivir phosphate, an antiviral, is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. Oseltamivir phosphate is hydrolyzed in the liver to its active form, oseltamivir carboxylate, which is an inhibitor of influenza viral neuraminidases essential for viral replication. Oseltamivir has a broad spectrum of activity against a range of influenza A and B subtypes with IC₅₀ values for neuraminidases measured from less than 1 nM to approximately 30 nM, depending on the virus subtype.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317,H319,H412
• P-Sätze: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable