Direkt zum Inhalt
Merck
Alle Fotos(1)

Dokumente

SMB00607

Sigma-Aldrich

Amoxicillin trihydrate: potassium clavulanate (4:1)

Synonym(e):

Amoxicillin Trihydrate: Potassium Clavulanate

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

UNSPSC-Code:
51285005
NACRES:
NA.85

Form

powder

Qualitätsniveau

200

Lagerbedingungen

(Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)

Farbe

white to yellow

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria

Wirkungsweise

cell wall synthesis | interferes

Lagertemp.

2-8°C

Allgemeine Beschreibung

Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.

Anwendung

Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.

Biochem./physiol. Wirkung

Amoxicillin trihydrate is a broad-spectrum, β-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by β-lactamases, it does not show activity against bacteria which produce these enzymes.

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin′s antibacterial activity against bacteria normally resistant to β-lactam antibiotics.

Verpackung

1G

Komponenten

Material is a powdered mixture of 4 parts amoxicillin trihydrate to 1 part potassium clavulanate.

Lagerung und Haltbarkeit

Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.

Piktogramme

FlameHealth hazard
GHS02,GHS08

Signalwort

Danger

Gefahreneinstufungen

Flam. Sol. 2 - Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1

Zusätzliche Gefahrenhinweise

EUH014,EUH044

Lagerklassenschlüssel

4.2 - Pyrophoric and self-heating hazardous materials

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Preparation and characterization of Sn/Zn/TiO2 photocatalyst for enhanced amoxicillin trihydrate degradation
Mohammadi R, et al.
Desalination and Water Treatment, 53(7), 1995-2004 (2015)
R N Brogden et al.
Drugs, 18(3), 169-184 (1979-09-01)
Amoxycillin, an acid stable semisynthetic penicillin shown to be effective against a wide range of infections when given orally, is now available for intramuscular and intravenous injection. Amoxycillin has an antibacterial spectrum and level of activity essentially the same as
In vitro antimicrobial activity of 6(D(-) -amino-p-hydroxyphenylacetamido) penicillanic acid, a new semisynthetic penicillin.
H C Neu et al.
Antimicrobial agents and chemotherapy, 10, 407-410 (1970-01-01)
Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
Di Liberto G, et al.
Cell (2018)
A P Ball et al.
Lancet (London, England), 1(8169), 620-623 (1980-03-22)
Clavulanic acid is an inhibitor of certain beta-lactamases, notably those enzymes which inactivate the penicillins and cause resistance of important bacteria to these antibiotics. Microbiological, pharmacological, and clinical studies show that clavulanic acid in combination with amoxycillin is effective and
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.