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Merck

31586

Supelco

Amoxicillin Trihydrat

VETRANAL®, analytical standard

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About This Item

Empirische Formel (Hill-System):
C16H19N3O5S · 3H2O
CAS-Nummer:
Molekulargewicht:
419.45
Beilstein:
7507120
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

clinical testing

Format

neat

Lagertemp.

2-8°C

SMILES String

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChIKey

MQXQVCLAUDMCEF-CWLIKTDRSA-N

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Allgemeine Beschreibung

Amoxicillin trihydrate is a β-lactam antibiotic. It is a broad-spectrum drug mostly administered orally.1 It is used to treat bacterial infections mainly caused by susceptible microorganisms.2
Chemical structure: ß-lactam

Anwendung

Verordnung (EU) Nr. 37/2010 vom 22. Dezember 2009 über pharmakologisch wirksame Stoffe und ihre Einstufung hinsichtlich der Rückstandshöchstmengen in Lebensmitteln tierischen Ursprungs
Amoxicillin trihydrate may be used as reference standard in stability study of Amoxicillin-Clavulanate in BACTEC Medium performed using HPLC.3
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Claudia Foti et al.
Molecules (Basel, Switzerland), 25(14) (2020-07-12)
A potentiometric and UV spectrophotometric investigation on Mn2+-ampicillin and Mn2+-amoxicillin systems in NaCl aqueous solution is reported. The potentiometric measurements were carried out under different conditions of temperature (15 ≤ t/°C ≤ 37). The obtained speciation pattern includes two species
Qian Zhao et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(7), 1605-1611 (2013-04-05)
This paper investigated the effects of selected common chemical species in natural waters (HCO3(-), NO3(-) and humic acids (HA)) on the photodegradation of amoxicillin (AMO) under simulated irradiation using a 300 W xenon lamp. Quenching experiments were carried out to
Fanny B Morel et al.
Neonatology, 103(3), 182-189 (2013-02-26)
It is suggested that antibiotherapy in infancy might program adult body composition and thus could be a determinant of obesity risk. Although not convincingly substantiated by existing literature, this assumption is plausible since antibiotics affect intestinal microbiota, whose composition in
Yu-Hsin Lin et al.
Biomaterials, 34(18), 4466-4479 (2013-03-19)
Helicobacter pylori is a significant human pathogen that recognizes specific carbohydrate receptors, such as the fucose receptor, and produces the vacuolating cytotoxin, which induces inflammatory responses and modulates the cell-cell junction integrity of the gastric epithelium. The clinical applicability of
Enrique Gómez et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 110(4), 267-273 (2013-03-29)
Although allergic drug reactions have been considered to be immediate (IgE mediated) or delayed (T-cell effector mechanisms), accelerated reactions have also been defined; however, they have not been sufficiently studied. To study the mechanisms involved in accelerated reactions to amoxicillin.

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