E2250

Ellagsäure

≥95% (HPLC), powder, from tree bark

• Synonym(e): 4,4′,5,5′,6,6′-Hexahydroxy-diphensäuredilacton, Alizaringelb, Benzoarsäure, Elagostasin, Gallogen, Lagistase
• Empirische Formel (Hill-System): C₁₄H₆O₈
• CAS-Nummer: 476-66-4
• Molekulargewicht: 302.19
• Beilstein: 47549
• EG-Nummer: 207-508-3
• MDL-Nummer: MFCD00006914
• UNSPSC-Code: 12352205
• PubChem Substanz-ID: 24894460
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: tree bark
• Assay: ≥95% (HPLC)
• Form: powder
• Haltbarkeit: 5 yr
• Löslichkeit: 1 M NaOH: 10 mg/mL
• Anwendung(en): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES String: Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
• InChI: 1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
• InChIKey: AFSDNFLWKVMVRB-UHFFFAOYSA-N
• Angaben zum Gen: human ... CSK(1445) , DYRK1A(1859) , GSK3B(2932) , SRC(6714) ; rat ... Lyn(81515) , Syk(25155)

Beschreibung

Allgemeine Beschreibung

Ellagic acid is a naturally occurring phenolic acid in many fruits and vegetables, as a secondary plant metabolite. It is commonly found in green tea, pomegranate, strawberries, blackberries, raspberries, and walnuts.

Anwendung

Ellagic acid has been used:

• to study the metabolism of dietary phenolic acids by Lactobacillus plantarum CECT 748T
• as a potential substrate for the high production of Lactobacillus plantarum tannase
• as a standard in the study to examine the phenolic components and anti-oxidant activity of nettle
• to study the links between dietary ellagic acid and epigenetic modulation of adipogenesis

Biochem./physiol. Wirkung

Ellagic acid has been found to exhibit antioxidant activity by virtue of having an inhibitory effect on the oxidation of low-density lipoproteins. This makes them have a cardioprotective effect on humans. In addition, it shows anticarcinogenic, antifibrotic, antiplasmodial, apoptotic, and chemopreventive activities as well.

Häufig vorkommendes pflanzliches Polyphenol, Inhibitor von Glutathione S-transferase. Wird für den Factor XIIa Assay in Plasma verwendet. Kontaktaktivierung bei der Blutgerinnung.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves