A0911

[Ile⁷]-Angiotensin III acetate salt hydrate

≥95% (HPLC)

• Synonym(e): Arg-Val-Tyr-Ile-His-Pro-Ile
• Empirische Formel (Hill-System): C₄₃H₆₈N₁₂O₉ · xC₂H₄O₂ · yH₂O
• Molekulargewicht: 897.08 (anhydrous free base basis)
• MDL-Nummer: MFCD11045994
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 329770638
• NACRES: NA.26

Eigenschaften

• product name: [Ile⁷]-Angiotensin III acetate salt hydrate, ≥95% (HPLC)
• Qualitätsniveau: 200
• Assay: ≥95% (HPLC)
• Form: powder
• Farbe: white
• Lagertemp.: −20°C
• SMILES String: O.CC(O)=O.CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(C)C)[C@@H](C)CC)C(O)=O
• InChI: 1S/C43H68N12O9.C2H4O2.H2O/c1-7-24(5)34(40(61)51-31(20-27-21-47-22-49-27)41(62)55-18-10-12-32(55)38(59)54-35(42(63)64)25(6)8-2)53-37(58)30(19-26-13-15-28(56)16-14-26)50-39(60)33(23(3)4)52-36(57)29(44)11-9-17-48-43(45)46;1-2(3)4;/h13-16,21-25,29-35,56H,7-12,17-20,44H2,1-6H3,(H,47,49)(H,50,60)(H,51,61)(H,52,57)(H,53,58)(H,54,59)(H,63,64)(H4,45,46,48);1H3,(H,3,4);1H2/t24-,25-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
• InChIKey: YXASJLHKVNKIRW-ZPJCNHGSSA-N

Beschreibung

Biochem./physiol. Wirkung

In [Ile7]-Angiotensin III (Ile7-AIII) the seventh amino acid of angiotensin III (phe) is replaced with isoleucine. [Ile7]-Angiotensin III (Ile7 AIII) is an angiotensin III (A III) receptor antagonist used to selectively block the action of Angiotensin III.

[Ile7]-Angiotensin III is (Ile7-Ang III) used as a peptide angiotensin receptor antagonist often in comparison with other Ang antagonists such as saralasin.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)