42602

Propionyl-L-carnitin

≥94.0% (HPLC), suitable for LC/MS

• Synonym(e): (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium Inneres Salz, L-Carnitin-propionylester, C3-Carnitin, Propanoyl-L-carnitin
• Empirische Formel (Hill-System): C₁₀H₁₉NO₄
• CAS-Nummer: 20064-19-1
• Molekulargewicht: 217.26
• MDL-Nummer: MFCD00870024
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 329756246
• NACRES: NA.26

Eigenschaften

• product name: Propionyl-L-carnitin, ≥94.0% (HPLC)
• Qualitätsniveau: 100
• Assay: ≥94.0% (HPLC)
• Form: powder or crystals
• Optische Aktivität: [α]/D -23±3°, c = 1 in H₂O
• Methode(n): LC/MS: suitable
• Verunreinigungen: ≤10% water (calcd. from elemental analysis)
• Farbe: white to off-white
• Lagertemp.: 2-8°C
• SMILES String: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• InChIKey: UFAHZIUFPNSHSL-MRVPVSSYSA-N

Beschreibung

Allgemeine Beschreibung

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

Anwendung

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem./physiol. Wirkung

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable