ABN411

Anti-Aquaporin-4 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: mouse, rat, human
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_036957
• UniProt-Hinterlegungsnummer: P47863
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... AQP4(361) ; mouse ... Aqp4(11829) ; rat ... Aqp4(25293)

Beschreibung

Allgemeine Beschreibung

Aquaporin-4 (AQP-4) is also known as Mercurial-insensitive water channel. AQP-4 is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. It is expressed predominantly in the mature brain, but also in the eye, kidney, intestine and lung. AQP-4 is a multi-pass membrane protein that is part of a complex along with MLC1, TRPV4, HEPACAM and ATP1B1.

Spezifität

This antibody recognizes the cytoplasmic domain of Aquaporin-4.

Immunogen

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat Aquaporin-4.

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Entwicklungsneurowissenschaft

Anti-Aquaporin-4 is an antibody targeting the Aquaporin-4 protein, validated for use in WB.

Qualität

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Aquaporin-4 in 10 µg of human brain tissue lysate.

Zielbeschreibung

~32 kDa observed

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Human brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable