810220P
Avanti
C6-NBD Galactosyl Ceramide
Avanti Polar Lipids 810220P, powder
Synonym(e):
N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-galactosyl-β1-1′-sphingosine
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C36H59N5O11
CAS-Nummer:
Molekulargewicht:
737.88
UNSPSC-Code:
12352211
NACRES:
NA.25
Empfohlene Produkte
Assay
>99% (TLC)
Form
powder
Verpackung
pkg of 1 × 250 μg (810220P-250ug)
Hersteller/Markenname
Avanti Polar Lipids 810220P
Versandbedingung
dry ice
Lagertemp.
−20°C
Verwandte Kategorien
Allgemeine Beschreibung
C6-NBD Galactosyl Ceramide is a fluorescent analog of the sphingolipid, galactosyl ceramide. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.
Anwendung
C6-NBD Galactosyl Ceramide is suitable for use as a substrate in neutral β-glycosylceramidase (GCase) activity assay.
Biochem./physiol. Wirkung
Galactosyl ceramide is also known as galactocerebroside and is produced in the lumen of the endoplasmic reticulum. Galactosyl ceramide is a vaccine adjuvant, it stimulates natural killer T (NKT) cells to increase secretion of T helper type 1 (Th1) and T-helper type 2 (TH2) cytokines. Galactosyl ceramide accumulation in excess is responsible for diseases such as Krabbe′s disease. Galactocerebroside is a precursor of 3′-sulfo-galactosylceramide, a vital sulfoglycolipid found in the brain and other organs.
Verpackung
5 mL Amber Glass Screw Cap Vial (810220P-250ug)
Rechtliche Hinweise
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Lagerklassenschlüssel
11 - Combustible Solids
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Distinct APCs explain the cytokine bias of $\alpha$-galactosylceramide variants in vivo
Bai LC, et al.
Journal of immunology (Baltimore, Md. : 1950), 188(7), 3053-3061 (2012)
Bernadette Breiden et al.
Annual review of biochemistry, 88, 461-485 (2019-06-22)
Glycosphingolipids are cell-type-specific components of the outer leaflet of mammalian plasma membranes. Gangliosides, sialic acid-containing glycosphingolipids, are especially enriched on neuronal surfaces. As amphi-philic molecules, they comprise a hydrophilic oligosaccharide chain attached to a hydrophobic membrane anchor, ceramide. Whereas glycosphingolipid
Yasuhiro Hayashi et al.
The Journal of biological chemistry, 282(42), 30889-30900 (2007-06-28)
Using C6-NBD-glucosylceramide (GlcCer) as a substrate, we detected the activity of a conduritol B epoxide-insensitive neutral glycosylceramidase in cytosolic fractions of zebrafish embryos, mouse and rat brains, and human fibroblasts. The candidates for the enzyme were assigned to the Klotho
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.