907383

Fmoc-L-Photo-Lysine

≥95%

• Synonym(e): N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N⁶-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
• Empirische Formel (Hill-System): C₂₆H₃₀N₄O₆
• CAS-Nummer: 2250437-42-2
• Molekulargewicht: 494.54
• UNSPSC-Code: 12352209

Eigenschaften

• Assay: ≥95%
• Form: solid
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: Fmoc
• Lagertemp.: 2-8°C

Beschreibung

Anwendung

Fmoc-L-Photo-Lysine is a diazirine-containing, Fmoc-protected lysine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907251.

Sonstige Hinweise

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable