901904

2-Di-tert-butylphosphin-2′,4′,6′-triisopropylbiphenyl

95%

• Synonym(e): tert.-Butyl-XPhos
• Empirische Formel (Hill-System): C₂₉H₄₅P
• CAS-Nummer: 564483-19-8
• Molekulargewicht: 424.64
• MDL-Nummer: MFCD06411306
• UNSPSC-Code: 12352002
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Form: powder or crystals
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings; reagent type: ligand
• mp (Schmelzpunkt): 148-151 °C (lit.); 150 °C
• Funktionelle Gruppe: phosphine
• SMILES String: CC(P(C(C=CC=C1)=C1C(C(C(C)C)=CC(C(C)C)=C2)=C2C(C)C)C(C)(C)C)(C)C
• InChI: 1S/C29H45P/c1-19(2)22-17-24(20(3)4)27(25(18-22)21(5)6)23-15-13-14-16-26(23)30(28(7,8)9)29(10,11)12/h13-21H,1-12H3
• InChIKey: SACNIGZYDTUHKB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

tBuXPhos [2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

Anwendung

tBuXPhos has been used in the preparation of [tBuXPhosAu(MeCN)]BAr₄F, a gold catalyst for the intermolecular [2+2] cycloaddition of terminal arylalkynes with substituted alkenes to form functionalized cyclobutenes with high regioselectivity.

Rechtliche Hinweise

Usage subject to US Patents 6307087 and 6395916.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable