464155

[3aR-[2(3′aR*,8′aS*),3′aβ,8′aβ]]-(+)-2,2′-Methylen-bis[3a,8a-dihydro-8H-inden[1,2-d]oxazol]

98%

• Empirische Formel (Hill-System): C₂₁H₁₈N₂O₂
• CAS-Nummer: 180186-94-1
• Molekulargewicht: 330.38
• MDL-Nummer: MFCD06797115
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24870145
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• Optische Aktivität: [α]22/D +353°, c = 3.7 in chloroform
• mp (Schmelzpunkt): 204-206 °C (lit.)
• SMILES String: C1[C@@H]2OC(CC3=N[C@H]4[C@@H](Cc5ccccc45)O3)=N[C@H]2c6ccccc16
• InChI: 1S/C21H18N2O2/c1-3-7-14-12(5-1)9-16-20(14)22-18(24-16)11-19-23-21-15-8-4-2-6-13(15)10-17(21)25-19/h1-8,16-17,20-21H,9-11H2/t16-,17-,20+,21+/m0/s1
• InChIKey: BDHSVQLSNIGJNC-ZCLUNYJNSA-N

Beschreibung

Anwendung

[3aR-[2(3′aR*,8′aS*),3′aβ,8′aβ]]-(+)-2,2′-Methylenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] is a C₂ symmetric chiral ligand based on bis(oxazoline) moiety, which can be used in enantioselective catalysis. It easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals. Copper complex of this chiral ligand can be utilized as a reusable catalyst in the cyclopropanation reaction between styrene and ethyl diazoacetate.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves