A0788

3-Aminobenzamid

≥99% (TLC)

• Synonym(e): 3-AB, 3-ABA
• Lineare Formel: H₂NC₆H₄CONH₂
• CAS-Nummer: 3544-24-9
• Molekulargewicht: 136.15
• EG-Nummer: 222-586-9
• MDL-Nummer: MFCD00007989
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278206
• NACRES: NA.77

Eigenschaften

• Assay: ≥99% (TLC)
• Form: powder
• Farbe: white to off-white
• mp (Schmelzpunkt): 115-116 °C (lit.)
• Löslichkeit: ethanol: 50 mg/mL, clear, light yellow; DMSO: soluble; H₂O: soluble (may require gentle heating)
• Lagertemp.: room temp
• SMILES String: NC(=O)c1cccc(N)c1
• InChI: 1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)
• InChIKey: GSCPDZHWVNUUFI-UHFFFAOYSA-N
• Angaben zum Gen: mouse ... Parp1(11545)

Beschreibung

Anwendung

3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies.

Biochem./physiol. Wirkung

3-Aminobenzamide enhances cell death, unscheduled DNA synthesis and repair replication by interrupting the rejoining of DNA strand breaks induced by both ionizing radiations and several alkylating agents. It has an ability to inhibit the activity of nuclear enzyme poly (ADP-ribose) synthetase (PARS). 3-Aminobenzamide exhibits protective action against myocardial reperfusion injury and local inflammation.

Leistungsmerkmale und Vorteile

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves