39410

4-(Dimethylamino)pyridin, polymergebunden

extent of labeling: ~3.0 mmol/g "DMAP" loading, matrix crosslinked with 2% DVB

• Synonym(e): 4-(Dimethylamino)pyridine on Polystyrene, DMAP on PS, polymer bound DMAP
• Empirische Formel (Hill-System): C₈H₈
• CAS-Nummer: 82942-26-5
• Molekulargewicht: 104.15
• MDL-Nummer: MFCD04041220
• UNSPSC-Code: 12352128
• PubChem Substanz-ID: 57649897
• NACRES: NA.22

Eigenschaften

• Eignung der Reaktion: reaction type: solution phase peptide synthesis
• Kennzeichnungsgrad: ~3.0 mmol/g "DMAP" loading
• Matrix: crosslinked with 2% DVB
• Anionenspuren: chloride (Cl^-): ≤5000 mg/kg

Beschreibung

Allgemeine Beschreibung

Polymer-bound 4-(dimethylamino)pyridine is used for improved derivatization of chiral and achiral aliphatic amines, amino alcohols and amino acids.

Anwendung

Polymer-bound 4-(dimethylamino)pyridine is used as a supported base in the Michael addition and nitrous acid elimination process step involved in the synthesis of thiophene-2-carboxylates using β-nitroacrylates as starting materials, under a general and efficient continuous flow-based protocol. It also serves as a supported catalyst in the preparation of ω-nitro esters starting from cyclic 2-nitro ketones under solid heterogeneous catalysis.(5)

Sonstige Hinweise

Polymer supported, recyclable acylation catalyst

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)