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Sigma-Aldrich

Diethylentriaminpentaessigsäure Gadolinium(III)-dihydrogensalz Hydrat

97%

Synonym(e):

Gadoliniumsäure

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About This Item

Empirische Formel (Hill-System):
C14H20GdN3O10 · xH2O
Molekulargewicht:
547.57 (anhydrous basis)
MDL-Nummer:
MFCD02092653
UNSPSC-Code:
12352300
PubChem Substanz-ID:
24863829

Qualitätsniveau

100

Assay

97%

Eignung der Reaktion

core: gadolinium
reagent type: catalyst

mp (Schmelzpunkt)

129 °C (dec.) (lit.)

SMILES String

[Gd+3].[H]O[H].OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C14H23N3O10.Gd.H2O/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;1H2/q;+3;/p-3

InChIKey

JBUMALASVLVYKI-UHFFFAOYSA-K

Verwandte Kategorien

Anwendung

Widely used metal ion complex for MRI used in the diagnosis of cerebral tumors, CNS diseases, hepatic tumors, pituitary adenomas, multiple sclerosis, and blood-brain barrier impairment.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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Evgeniya Goldman et al.
Nanotechnology, 28(43), 43LT01-43LT01 (2017-09-06)
Despite advances in cancer therapy, treating cancer after it has metastasized remains an unmet clinical challenge. In this study we demonstrate that 100 nm liposomes target triple-negative murine breast-cancer metastases post intravenous administration. Metastatic breast cancer was induced in BALB/c
Christof Karmonik et al.
World neurosurgery, 105, 775-782 (2017-06-19)
Hemodynamics in cerebral aneurysms are currently investigated toward clinical efficacy using nonstandardized computational simulation techniques. At the same time, flow patterns and velocities are accessible by 4-dimensional phase contrast magnetic resonance imaging (4D pcMRI). Complexity of protocol design and imaging
Rui Wang et al.
PloS one, 10(6), e0130207-e0130207 (2015-06-13)
Although European Society of Urogenital Radiology proposed the potential of multiparametric magnetic resonance imaging (MP-MRI) as a tool in the diagnostic pathway for prostate cancer (PCa) and published a unified scoring system named Prostate Imaging Reporting and Data System (PI-RADS
K Ohtomo et al.
Radiology, 163(1), 27-31 (1987-04-01)
Thirty-six patients with hepatic tumors (28 hepatocellular carcinomas, seven cavernous hemangiomas, one metastatic tumor) were examined with serial magnetic resonance (MR) imaging, after a bolus intravenous injection of 0.05 mmol/kg gadolinium-diethylenetriaminepentaacetic acid. A typical MR imaging pattern for hemangiomas (present
A J Dwyer et al.
Radiology, 163(2), 421-426 (1987-05-01)
To assess the role of magnetic resonance imaging in the evaluation of adrenocorticotropic-hormone (ACTH)-producing pituitary adenomas, and the effect of intravenously administered gadolinium-diethylenetriaminepentaacetic acid (DTPA) on lesion/pituitary contrast, imaging was performed in 13 patients with clinical and chemical evidence of
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