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HPLC Analysis of Phenolic Antioxidants on Ascentis® Express C18 2.7 μm

HPLC Analysis of Phenolic Antioxidants on Ascentis® Express C18 2.7 μm application for HPLC

CONDITIONS

column

Ascentis Express C18, 10 cm x 3.0 mm I.D., 2.7 μm partcles (53814-U)

mobile phase

[A] water; [B] acetonitrile; [C] 2-propanol;

gradient

Constant 43% C; 37 to 55% B in 3.6 min; held at 55% B for 2.4 min

flow rate

1 mL/min

pressure

4970 psi (343 bar)

column temp.

40 °C

detector

UV, 280 nm

injection

5 μL

sample

5 standards at 20 μg/mL

Description

Analysis Note

Phenolic Antioxidants are added to polyers for controlling their degradation process. Irgafos 168, Irganox 1010, Ethanox 330, Irganox 1076, BHT, and Irgafos 168 are often used as antioxidants to prevent the degradation of polypropylene polymer formulations. This HPLC method is for the quantitation of an additive or mix of additives in a polymeric material.

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany