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Merck

TNFAIP3

tumor necrosis factor, alpha-induced protein 3

Synonyms:
A20, OTUD7C, TNFA1P2
Species:
UniProtKB ID:
Gene ID:
  • Human(7128) Summary: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
  • Mouse(21929) tumor necrosis factor, alpha-induced protein 3
  • Rat(683206) tumor necrosis factor, alpha-induced protein 3
  • Zebrafish(564497) tumor necrosis factor, alpha-induced protein 3
  • Horse(100073197) tumor necrosis factor, alpha-induced protein 3
  • domestic cat(101083682) tumor necrosis factor, alpha-induced protein 3
  • dog(484006) tumor necrosis factor, alpha-induced protein 3
  • chicken(421684) tumor necrosis factor, alpha-induced protein 3
  • domestic guinea pig(100720503) tumor necrosis factor, alpha-induced protein 3
  • cow(508105) tumor necrosis factor, alpha-induced protein 3
  • sheep(101113156) tumor necrosis factor, alpha-induced protein 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TNFAIP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TNFAIP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-TNFAIP3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution, ab1,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-A20 Mouse mAb (59A426), liquid, clone 59A426, Calbiochem®,
Species Reactivity
human
Application
Anti-TNFAIP3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
A20 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥20% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TNFAIP3,
Species
human
MISSION® esiRNA, targeting mouse Tnfaip3,
Species
mouse