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Merck

SLC29A1

solute carrier family 29 (equilibrative nucleoside transporter), member 1

Sinónimos:
ENT1
Especie:
ID UniProtKB:
ID del gen:
  • Human(2030) Summary: This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(63959) solute carrier family 29 (nucleoside transporters), member 1
  • Rat(63997) solute carrier family 29 (equilibrative nucleoside transporter), member 1
  • cow(510932) solute carrier family 29 (nucleoside transporters), member 1
  • sheep(101117541) solute carrier family 29 (nucleoside transporters), member 1
  • Goat(100861005) solute carrier family 29 (nucleoside transporters), member 1
  • Domestic Rabbit(100357908) solute carrier family 29 (nucleoside transporters), member 1
  • naked mole-rat(101701245) solute carrier family 29 (nucleoside transporters), member 1
  • domestic guinea pig(100730207) solute carrier family 29 (nucleoside transporters), member 1
  • chicken(421439) solute carrier family 29 (nucleoside transporters), member 1
  • Horse(100055498) solute carrier family 29 (nucleoside transporters), member 1
  • dog(442966) solute carrier family 29 (nucleoside transporters), member 1
  • domestic cat(101095579) solute carrier family 29 (nucleoside transporters), member 1

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
2′-Deoxyuridine, ≥98.5%,
Especie
mouse
3′-Azido-3′-deoxythymidine, ≥98% (HPLC),
Especie
mouse
S-(4-Nitrobenzyl)-6-thioinosine, ≥98%, solid,
Especie
human
Dipyridamole, ≥98% (HPLC),
Especie
mouse, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HENT1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP120, affinity isolated antibody,
Reactividad de especies
human, rabbit, rat
Aplicación
immunohistochemistry
Anti-SLC29A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
3′-Azido-3′-deoxythymidine, ≥98% (HPLC),
Especie
mouse
S-(4-Nitrobenzyl)-6-thioinosine, ≥98%, solid,
Especie
human
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SLC29A1,
Especie
human